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The overall number of events are reduced by syt IV upregulated in syt I targeted cells, but without any loss of the small or large diameter vesicle populations. Cumulative distribution histograms of the cubed root of the quantal content (pC)1/3 are shown for untreated and forskolin-treated control (A, C) and shRNA-syt I knockdown (B, D) cells. The mean of each histogram is displayed on the individual graph generated with 48 bins.
