TABLE 2.
IVM, 3 μM | EtOH, 50 mM | ATP EC10 Range | |
---|---|---|---|
% Potentiation | % Inhibition | μM | |
Met (WT) | 208 ± 24 | 22.0 ± 1.6 | 1.0–1.2 |
Ala | 1154 ± 51 | 9.3 ± 4.6 | 0.5–0.8 |
Val | 737 ± 42 | 6.5 ± 3.7 | 0.8–1.0 |
Phe | 324 ± 25 | 19.0 ± 3.5 | 0.8–1.0 |
Trp | 531 ± 96 | 5.9 ± 2.5 | 0.25–0.3 |
Gln | 508 ± 77 | 4.0 ± 5.5 | 0.6–0.8 |
Glu | 15.5 ± 5.9 | −1.0 ± 3.6 | 0.6–0.8 |
Arg | −4.8 ± 1.8 | 0.8 ± 1.4 | 0.1–0.2 |