Plasma total ceramide concentrations, delta body weight, adipocyte size, and
arterial blood pressure in C57BL/6J mice on low-fat or high-fat diet with or
without amitriptyline treatment. Data are arithmetic means ± S.E.
(n = 4–12/group) of plasma total ceramide
concentrations (A), delta body weight (B), adipocyte size (original magnification,
100×) (C), and mean arterial blood pressure (D) in LFD- or HFD-fed
C57BL/6J mice with or without amitriptyline treatment. *, P
< 0.05, significant difference compared with the values from mice
receiving the LFD. #, P < 0.05, significant
difference compared with the values from mice receiving the HFD. Scale bar, 50
μm.