TABLE 1.
Estimated Ki (μM) values for murine Oat6- and Oat3-mediated estrone sulfate transport
Oat6 and Oat3 values are reported as mean ± S.E. Significance between Oat6 and Oat3 Ki values is indicated as *, P < 0.05; **, P < 0.01; and ***, P < 0.001.
| Compound | Oat6 | Oat3 | Ki Ratio (Oat6/Oat3) |
|---|---|---|---|
| Probenecid | 8.3 ± 2.5a | 0.8 ± 0.2 | 10.4 |
| Salicylate | 49.0 ± 4.4a | 342.7 ± 93.1* | 0.1 |
| 2,4-D | 15.7 ± 2.0a | 2.0 ± 0.4** | 7.9 |
| Penicillin G | 1450 ± 480a | 60.7 ± 5.9* | 23.9 |
| HVA | 3.0 ± 0.5 | 134.5 ± 27.0** | 0.02 |
| HIAA | 48.9 ± 10.3 | 67.8 ± 7.2 | 0.7 |
| DOPAC | 61.4 ± 7.1 | 346.7 ± 97.9* | 0.2 |
| DHEAS | 38.8 ± 3.1 | 3.8 ± 1.1*** | 10.2 |
| HA | 59.9 ± 4.9 | 79.3 ± 4.0* | 0.8 |
a
Values were taken from Schnabolk et al. (2006).