Table 3.

Cognitive Impairment, Depressive Symptoms, and Relative Risk of 2-Year Functional Decline, Multivariate Results, by Baseline Activities of Daily Living Status (N = 5,697)

		Relative Risk (95% Confidence Interval)*
Model	Participant Group	Dependent at Baseline (n = 525)	Independent at Baseline (n = 5,172)
3	Cognitive impairment	1.9 (1.3–2.7)	2.2 (1.6–2.8)
	No impairment	1	1
	Depressive symptoms	0.8 (0.5–1.2)	1.7 (1.3–2.2)
	No depressive symptoms	1	1
4	Cognitive impairment alone	1.9 (1.2–2.8)	2.3 (1.7–3.1)
	Depressive symptoms alone	0.6 (0.3–1.3)	1.9 (1.3–2.6)
	Cognitive impairment and depressive symptoms	1.5 (0.8–2.6)	2.4 (1.4–3.7)
	Neither depressive symptoms nor cognitive impairment	1	1

^*Full adjustment for age, education, race, gender, marital status, medical comorbidities, smoking and alcohol use, Medicare insurance, and income.