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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Circ Cardiovasc Genet. 2009 Aug 22;2(5):476–482. doi: 10.1161/CIRCGENETICS.109.883595

Figure 1. Linkage Disequilibrium Structure for EPHB4 Locus.

Figure 1

EPHB4 SNPs are represented in order on the chromosome. The strength of linkage disequilibrium between SNPs is represented both numerically and by the depth of shading (r2) computed using all genotype data from the 248 BAVM patients. Two haplotype blocks exist in this EPHB4 region: block 1, SNPs rs314346 – rs144173, and block 2, rs314308 – rs2247445.