Table 2. Genotype Frequencies of EPHB4 Polymorphisms in Phase I BAVM Patients by ICH Presentation.
| ICH n (%) |
Non-ICH n (%) |
Total n (%) |
P value | |
|---|---|---|---|---|
| rs314346 | ||||
| TT | 7 (12.5) | 26 (28.9) | 33 (22.6) | 0.056 |
| CT | 34 (60.7) | 48 (53.3) | 82 (56.2) | |
| CC | 15 (26.8) | 16 (17.8) | 31 (21.2) | |
| rs314353 | ||||
| GG | 9 (16.1) | 36 (40.0) | 45 (30.8) | 0.010 |
| AG | 37 (66.1) | 42 (46.7) | 79 (54.1) | |
| AA | 10 (17.9) | 12 (13.3) | 22 (15.1) | |
| rs2230585 | ||||
| GG | 18 (32.1) | 38 (42.2) | 56 (38.4) | 0.274 |
| AG | 28 (50.0) | 43 (47.8) | 71 (48.6) | |
| AA | 10 (17.9) | 9 (10.0) | 19 (13.0) | |
| rs144173 | ||||
| GG | 14 (25.0) | 37 (41.1) | 51 (34.9) | 0.116 |
| AG | 32 (57.1) | 43 (47.8) | 75 (51.4) | |
| AA | 10 (17.9) | 10 (11.1) | 20 (13.7) | |
| rs314308 | ||||
| CC | 39 (69.6) | 41 (45.6) | 80 (54.8) | 0.006 |
| CT | 15 (26.8) | 33 (36.7) | 48 (32.9) | |
| TT | 2 (3.6) | 16 (17.8) | 18 (12.3) | |
| rs2250818 | ||||
| CC | 25 (44.6) | 51 (56.7) | 76 (52.1) | 0.352 |
| CT | 27 (48.2) | 33 (36.7) | 60 (41.1) | |
| TT | 4 (7.1) | 6 (6.7) | 10 (6.8) | |
| rs314313 | ||||
| TT | 39 (69.6) | 40 (44.4) | 79 (54.1) | 0.012 |
| CT | 14 (25.0) | 41 (45.6) | 55 (37.7) | |
| CC | 3 (5.4) | 9 (10.0) | 12 (8.2) | |
| rs2247445 | ||||
| GG | 25 (44.6) | 52 (57.8) | 77 (52.7) | 0.303 |
| AG | 27 (48.2) | 33 (36.7) | 60 (41.1) | |
| AA | 4 (7.1) | 5 (5.6) | 9 (6.2) | |
P value, χ2 test