Table 1.
Characteristic at ART initiation | Frequency** | Percentage |
---|---|---|
Sex | ||
Male | 699 | 50.18 |
Female | 694 | 49.82 |
WHO Clinical stage | ||
1 or 2 | 422 | 32.61 |
3 or 4 | 872 | 67.39 |
Severity of immunosuppression (WHO) | ||
Mild or not significant | 158 | 11.55 |
Advanced | 90 | 6.58 |
Severe | 1120 | 81.87 |
Viral load | ||
>=100 000 copies/ml | 772 | 58.31 |
<100000 copies/ml | 552 | 41.69 |
Weight-for-age z score† | ||
>=−2SD | 668 | 49.34 |
−2 to −3SD | 308 | 22.75 |
< −3SD | 378 | 27.92 |
Height-for-age z score† | ||
>=−2SD | 430 | 32.02 |
−2 to −3SD | 401 | 29.86 |
< −3SD | 512 | 38.12 |
TB treatment at ART initiation | ||
No | 1041 | 74.68 |
Yes | 353 | 25.32 |
Age at ART initiation | ||
< 1.5 years | 262 | 18.79 |
1.5 – 2.9 years | 239 | 17.14 |
3.0 – 4.9 years | 254 | 18.22 |
5.0 – 7.9 years | 349 | 25.04 |
8.0 – 15.0 years | 290 | 20.8 |
Time on ART in months median (IQR) | 25.2 | (17.9 to 33.5)‡ |
Children were included if they had at least 6 months of follow-up on ART and at least a pre-HAART and a 6-month measurement needed to estimate the six-month gain. Those children were part of a cohort of HIV-infected children who were initiated on ART at HSCC between April, 2004 and March, 2008. IQR = interquartile range.
Gender specific weight- and height- for-age z score were obtained by plotting the weight measurements at baseline against the World Health Organization (WHO) weight- and height-for-age charts for children <= 5years and against the Center for Disease and Control prevention (CDC) for children older than 5 years.
Minimum = 6 months, Maximum = 47 months.
Totals varies by baseline characteristics due to missing data