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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Cancer Res. 2010 Jan 12;70(2):609–620. doi: 10.1158/0008-5472.CAN-09-2327

Figure 6.

Figure 6

Expression of multiple HDACi-induced genes is reduced in primary colon tumors relative to adjacent normal mucosa. (A) The percentage of HDACi-induced and (B) un-induced (control) sequences significantly over or underexpressed in colon tumors. (C) Identity of the 9 genes induced by HDACi and significantly repressed in colon tumors relative to normal colonic epithelium (*P<0.05). (D) Immunohistochemical validation of reduced expression of ATF3 and metallothionein in normal colon and colon tumors. Images downloaded from the publicly available protein atlas database (www.proteinatlas.org) as per the image use policy of protein atlas.