(A) Compiled polypeptide patterns of the patients and controls examined. Shown are compiled patterns consisting of all samples from patients with a subsequent CAD event and from controls with no CAD event during the observation period. The molecular mass (0.8–25 kDa, on a logarithmic scale) is plotted against normalized migration time (18–45 min). Signal intensity is encoded by peak height and color. (B) Distribution of the biomarkers for CAD in the same patients as shown in (A), with signal intensity amplified 10-fold in comparison to (A). (C) (Top panels) Compiled polypeptide patterns of all subjects in the study, according to albuminuria (29 normoalbuminuric, six microalbuminuric, and three macroalbuminuric patients). (Bottom panels) Distribution of the 33 biomarkers for chronic renal disease (RD1) in the three groups, with signal intensity amplified 10-fold in comparison to top panels. (D) (Top panels) Compiled polypeptide patterns of all subjects in the study, according to metabolic status (30 with diabetes, eight without diabetes). (Bottom panels) Distribution of the 261 biomarkers for diabetes defined previously in the two groups, with signal intensity amplified 10-fold in comparison to top panels.