Table 2. DA.PVG-Eae23 is protected from EAE compared to DA.

	Females Mean (SD)		Males Mean (SD)
	DA (N = 12)	D.P-Eae23 (N = 13)	DA (N = 22)	D.P-Eae23 (N = 21)
Incidence	92%	69%	82%	76%
Day of Onset	14.8 (8.3)	22.5 (12.9)	19.6 (10.4)	21.9 (11.3)
Max EAE Score	2.8 (1.4)	1.5 (1.3)*	2.6 (1.6)	1.7 (1.2)*
Duration	19.7 (8.6)	10.1 (9.5)*	15.8 (8.9)	11.7 (10.2)
Cumulative EAE score	50.7 (32.7)	15.0 (17.0)**	38 (28)	23 (23.9)

Mann-Whitney U-test was used to compare clinical phenotypes between parental DA and DA.PVG-Eae23; p values ≤0.05 were considered significant, indicated by

* = p<0.05;

** = p<0.01. Abbreviations: SD  =  standard deviation.