Table 3. Expected congenic phenotype values based on the (DA × PVG.1AV1) G10 AIL.
Congenic Strain | AIL Genotype | Expected Phenotype Value | ||||||
Eae23a | Eae23b | WL0b | INC a | ONS b | MAX b | DUR b | CUM b | |
DA (62) | DA | DA | 0.95 | 17% | 35.88 | 0.36 | 1.67 | 3.59 |
D.P-Eae23 (98) | PVG | PVG | 3.45** | 47%*** | 27.59*** | 1.35*** | 7.93*** | 19.36*** |
Eae23-Het (30) | DA/PVG | DA/PVG | 2.57 | 35%* | 30.61 | 1.03 | 5.9 | 14.29 |
Rats that matched the genotype combinations captured in the congenic strains were selected from the AIL cohort. The number of AIL rats that were used to generate the expected phenotype value for each congenic strain is indicated in parenthesis. Rats with DA genotype were compared to rats with either PVG or heterozygous genotype in Eae23;
= Fisher's Exact Test,
= Mann-Whitney U-test. p values ≤0.05 were considered significant, indicated by
* = p<0.05;
** = p<0.01;
*** = p<0.001.