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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: J Invest Dermatol. 2010 Jun 17;130(10):2489–2496. doi: 10.1038/jid.2010.162

Figure 2. Proliferative history of two normal and two keloid strains and effect of in vitro aging on HC-mediated growth stimulation of normal fibroblasts.

Figure 2

Each cell culture was initiated from the previous cycle on day indicated. Cell counts are averages of duplicate cultures and expressed as log2 of cell number so that each unit equals one population doubling. (a) normal strain 130; (b) normal strain 21; (c) keloid strain 33; (d) keloid strain 50; (e) effect of HC on maximum cell density of strain 21 during the 4th culture cycle prior to a change in growth rate; (f) effect of HC on maximum cell density of strain 21 during the 7th culture cycle after the growth rate change. Control (circles); HC (triangles).