Table 2.
References | Race | Number of patients | Naïve | Formula of therapy | Duration of treatment (weeks) | SVR (%) |
---|---|---|---|---|---|---|
Liu et al. [17] | Asian (Taiwan) | 308 | Yes | PegIFN-α-2a 180 μg/week + RBV 1,000–1,200 mg/day | 48 | 76 |
PegIFN-α-2a 180 μg/week + RBV 1,000–1,200 mg/day | 24 | 56 | ||||
Yamada et al. [100] | Asians (Japan) | 192 | Yes | PegIFN-α-2a 180 μg/week + RBV 600–1,000 mg/day | 48 | 59.4 |
PegIFN-α-2a 180 μg/week + placebo | 48 | 24.0 | ||||
Muir et al. [16] | Blacks | 100 | PegIFN-α-2b 1.5 μg/kg per week + RBV 800–1,000 mg/day 48 | 19 | ||
Non-Hispanic Whites | 100 | PegIFN-α-2b 1.5 μg/kg per week + RBV 800–1,000 mg/day 48 | 52 | |||
Rodriguez-Torres et al. [15] | Latino | 269 | Yes | PegIFN-α-2a 180 μg/week + RBV 1,000–1,200 mg/day | 48 | 34 |
Non-Latino | 300 | Yes | PegIFN-α-2a 180 μg/week + RBV 1,000–1,200 mg/day | 48 | 49 | |
Hepburn et al. [14] | Asians | 36 | IFN + RBV | 48 | 61 | |
Whites | 496 | 39 | ||||
Hispanics | 79 | 23 | ||||
African-Americans | 50 | 14 | ||||
Conjeevaram et al. [13] | African-Americans | 19 | Yes | PegIFN-α-2a 180 μg/week + RBV 1,000–1,200 mg/day | 48 | 28 |
Caucasian Americans | 20 | 52 |
Naïve treatment-naïve