Fig. 2.

Pretreatment with different doses of rhIL-2 in Con A-induced hepatitis. Mice were treated with PBS or IL-2 before Con A administration. a A single injection of indicated high doses of IL-2 were injected to mice 6 h before Con A injection. b Multiple injections of indicated low doses of IL-2 were injected to mice in 24 h for four times (every 8 h) before Con A injection. Sera were collected 24 h after Con A injection and serum ALT levels were measured. Values in a and b are shown as means ± SEM (n = 3) from 3 mice in three independent experiments. ^*P < 0.05 versus PBS. ^**P < 0.001 versus PBS