Fig. 3.
Treatment with high or low doses of rhIL-2 at different time courses in Con A-induced hepatitis. Mice were treated with PBS or IL-2 before or after Con A. a A single injection of high dose of IL-2 (IL-2hi, 50,000 U) were injected to mice at indicated time points. The time of Con A injection was identified as 0 h. Sera were collected 24 h after Con A injection. b Multiple injections of low dose of IL-2 (IL-24lo, 5,000 U) were injected to mice in 24 h for four times (every 8 h) at indicated time points. Sera were collected 24 h after Con A injection. Values in a and b are shown as means ± SEM (n = 3) from 3 mice in three independent experiments. **P < 0.001 versus PBS