Table 1.
Age | n | P mean | f H (min−1) | ΔP mean (kPa) Ang II Dose (ng/kg) | |||||
---|---|---|---|---|---|---|---|---|---|
100 | 250 | 500 | 1,000 | 2,000 | 1,000 s | ||||
13 | 6 (7) | 0.78 ± 0.05 | 239 ± 3 | 0.12a | 0.21ab | 0.26bc | 0.31c | 0.41d | 0.29c |
17 | 8 (8) | 1.94 ± 0.05 | 259 ± 3 | 0.21a | 0.30a | 0.46b | 0.74c | 0.89c | 0.85c |
19 | 8 (10) | 2.31 ± 0.08 | 250 ± 3 | 0.23NS | 0.44a | 0.61a | 0.99b | 1.20b | 1.08b |
20 | 7 (6) | 2.75 ± 0.07 | 268 ± 4 | 0.62a | 0.86a | 0.83a | 1.59b | 1.69b | 1.32b |
21 | 6 (6) | 2.85 ± 0.10 | 287 ± 4 | 0.43a | 0.96b | 1.14b | 1.69c | 1.64c | 1.56c |
Different letters between pressure responses to the increasing doses of Ang II indicate significant (p < 0.05) differences in the response intensity within an age group. All ΔP mean were significant (p < 0.05) unless noted by NS. The data are presented as mean ± SE. The number of embryos treated with a single injection of Ang II is indicated in parenthesis