TABLE 1.
Treatment | Insulin (ng/ml) | Somatostatin (pg/ml) |
---|---|---|
5.5 mmol/1 glucose | 7.58 ± 0.74 | 40.42 ± 2.52 |
5.5 mmol/1 glucose 100.0 ng/ml leptin |
5.47 ± 0.68* | 40.91 ± 5.77 |
11.0 mmol/1 glucose | 8.63 ± 0.48 | 45.31 + 4.50 |
11.0 mmol/1 glucose 100.0 ng/ml leptin |
7.53 ± 0.31† | 39.65 ± 3.37 |
11.0 mmol/1 glucose 10.0 nmol/1 GLP-I |
13.87 ± 1.01 | 59.19 ± 6.11 |
11.0 mmol/1 glucose 10.0 nmol/1 GLP-I 100.0 ng/ml leptin |
14.06 ± 1.17 | 59.98 ± 1.88 |
Data are means ± SE; n = 7; GLP-I, n = 4.
P < 0.0007
P < 0.022 compared with controls in the absence of leptin using Student’s paired t test.