Table 1.
Clinical characteristics of latent autoimmune diabetes in adults (LADA) patients with the human leucocyte antigen (HLA)-DQB1*0302 Type 1 diabetes risk allele and patients without the HLA-DQB1*0302 allele.
| Type 1 diabetes risk HLA*DQB1*0302 | ||
|---|---|---|
| Variables | Yes | No |
| n | 21 | 25 |
| Age (years) | 52 (30–65) | 59 (43–69) |
| Males (n) | 19 | 19 |
| GADA (U/ml) | 97 (32–4487) | 56 (38–296 997) |
| IA-2A positive (n) | 5 | 1 |
| IAA | 1 | 1 |
| BMI (kg/m2) | 26 (20–34) | 28 (21–39) |
| HbA1c% | 6·5 (5·1–10·9) | 5·9 (4·6–9·9) |
| P-glucose (mmol/l) pre-Sustacal | 8·5 (5·5–15·8) | 8·0 (5·9–17·4) |
| P c-peptide (nmol/l) pre-Sustacal | 0·6 (0·3–1·6) | 0·7 (0·3–1·8) |
| P c-peptide (nmol/l) post-Sustacal | 1·4 (0·5–3·9) | 1·6 (0·8–5·1) |
BMI, body mass index; GADA, glutamic acid decarboxylase 65 autoantibodies; HbA1c, haemoglobin A1c; IAA, insulin autoantibodies.