Table 1.
SVR (n = 20) | Non-SVR (n = 14) | |
---|---|---|
Age (years) | 48 (21–56) | 48 (21–66) |
Sex(male/female) | 11/9 | 9/5 |
HCV genotype 1/2/3 | 11/0/9 | 9/2/3 |
Serum HCV RNA (log10 copies/ml) | 5·44 (3·97–6·55) | 5·32 (4·20–6·11) |
Serum ALT(U/ml) | 123 (30–449) | 107 (25–224) |
Liver histology(Scheuer) | ||
Fibrosis 1/2/3/4 | 8/7/1/4 | 3/5/3/3 |
IFN-γ responses* | ||
HCV core | 44 (0–104) | 43 (0–146) |
HCV NS3 | 43 (0–91) | 29 (0–180) |
CMV | 53 (0–376) | 66 (14–410) |
Interferon (IFN)-γ responses are expressed as spots per 2 × 105 peripheral blood mononuclear cells. ALT, serum alanine aminotransferase; CMV, cytomegalovirus; SVR, sustained virological response.