Figure 1.

Effects of ketanserin (K) on the stepping pattern induced by ES in decerebrated cats. EMG recordings from the left VL (LVL), left St (LSt), left LG (LLG), left TA (LTA), right LG (RLG), and right TA (RTA) muscles during stepping at a belt speed of 0.3–0.4 m/s induced by ES alone (A) or by ES plus K administration (ES+K) (B). Note that the administration of K markedly reduces the EMG bursting in all muscles. C, Videographic recordings of one step cycle on the treadmill at a belt speed of 0.3–0.4 m/s during ES and ES+K are shown. Note the robust step kinematics induced by ES, whereas little movement of the limb is observed after K administration. D, Change of mean amplitude of the EMG bursts and the mean EMG burst duration in VL, St, LG, and TA of the left hindlimb during ES after administration of K relative to that seen for ES alone are shown. *p < 0.05, significant difference between ES alone and ES+K.