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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Science. 2010 Apr 9;328(5975):243–248. doi: 10.1126/science.1178590

Fig. 2. TCR sequence and comparison of TN T cells with wildtype and transgenic mice.

Fig. 2

(A) Schematic representation of the V(D)J rearrangements at the TCR-α (top panel) and TCR-β locus (lower panel) in TN mice. Top row represents wildtype configuration and some regions for orientation (data based on www.ensembl.org). (B and C) Representative flow cytometric analysis of splenocytes from wildtype, T57 and OT-I mice (B) or wildtype, G4 and 2C Rag−/− mice (2 mice per genotype were analyzed) (C).