Fig 2.

Early T-cell precursor (ETP) gene expression signature identifies a subset of patients with a poor prognosis. (A) Hierarchical clustering analysis of gene expression data based on a set of genes differentially expressed in ETP T-cell acute lymphoblastic leukemia (T-ALL)²² classifies 14 of our 40 patients as harboring the ETP gene expression signature. (B, C) Kaplan-Meier analyses of event-free survival and overall survival in T-ALL with or without the ETP gene expression signature. Tick marks indicate patients still at risk.