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. 2010 Jul 12;28(24):3851–3857. doi: 10.1200/JCO.2010.29.5477

Table 4.

Postsurgical Complications Among Patients Who Completed All Four Courses of Neoadjuvant Chemotherapy and Then Underwent Lymphadenectomy (n = 22)

Timing and Grade of Complication* Type of Postsurgical Complication
Noninfectious Wound Separation or Skin Breakdown
Hemorrhage or Bleeding
Skin Infection
Lower Extremity Edema
Edema in Trunk and/or Genitalia
Soft Tissue Necrosis
Seroma
No. % No. % No. % No. % No. % No. % No. %
Early (within 30 days of surgery)
    Grade 4 0 0 1 4.5 0 0 0 0 0 0 0 0 0 0
    Grade 3 2 9.1 2 9.1 1 4.5 0 0 1 4.5 2 9.1 0 0
    Grade 1 or 2 3 13.6 0 0 0 0 6 27.3 2 9.1 2 9.1 1 4.5
Delayed (more than 30 days after surgery)
    Grade 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0
    Grade 3 0 0 0 0 1 4.5 0 0 0 0 0 0 3 13.6
    Grade 1 or 2 0 0 0 0 2 9.1 5 22.7 2 9.1 0 0 0 0
*

All complications were graded by using the Common Terminology Criteria for Adverse Events, version 3.

This grade 4 hemorrhage was noted on postoperative day 2 and required operative intervention but was no further issue.