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. 2010 Jul 8;117(2):457–465. doi: 10.1093/toxsci/kfq204

TABLE 2.

Biological Pathways Influenced by HD

Pathway number Pathway name Odds ratio p Value
All Ingenuity molecular and cellular function pathways 2.0103 0.0073
18 Cell cycle/cell division process 2.7952 0.0130
22 Cell cycle/G1/S phase transition 6.8666 0.0378
26 Cell death/apoptosis 1.9380 0.0527
6 Carbohydrate metabolism/metabolic process 3.6211 0.0563
17 Cell cycle/cell cycle progression 2.5197 0.0591
81 DNA replication, recombination, and repair/metabolism 3.3731 0.0664
79 DNA replication, recombination, and repair/fragmentation 4.7104 0.0725
19 Cell cycle/cell stage 2.3598 0.0731
96 Lipid metabolism/metabolism 3.0340 0.0845
78 DNA replication, recombination, and repair/degradation 4.0847 0.0920
62 Cellular development/hypertrophy 4.0534 0.0932
71 Cellular growth and proliferation/hypertrophy 4.0534 0.0932
95 Lipid metabolism/metabolic process 2.8567 0.0966
42 Cell signaling/protein kinase cascade 2.6618 0.1126
72 Cellular growth and proliferation/proliferation 1.6778 0.1163
27 Cell death/cell death 1.6345 0.1166
7 Carbohydrate metabolism/quantity 3.3715 0.1256
61 Cellular development/growth 3.3498 0.1269
97 Lipid metabolism/modification 3.3283 0.1282
58 Cellular development/developmental disorder 3.2862 0.1308