FIG. 3.

Effects of antiretroviral treatment on vascular aconitase activity. The enzymatic activity of aconitase was determined in segments of aortic tissue from animals treated for 5 days with antiretrovirals. Results are means ± SEM. ANOVA with Dunnett's multiple comparison test revealed that compared with controls, antiretroviral treatment alone significantly decreased aconitase activity. Treatment with MnTMPyP alone or MnTMPyP + antiretrovirals did not alter aconitase activities compared with controls. Asterisk denotes significance compared with controls.