Table 1.
Obesity, Physical Activity, and Diet Associations With Breast, Ovarian, and Endometrial Cancer Overall or Cancer-Specific Survival
| Lifestyle Factor | Survival |
||
|---|---|---|---|
| Breast | Ovary* | Endometrium* | |
| Obesity/overweight | ↓↓† | ⇆ | ↓ |
| Underweight | ↓ | ? | ? |
| Weight gain | ? | ↑ | ? |
| Weight loss | ↓‡ | ↓ | ? |
| Physical activity | ↑ | ? | ? |
| Dietary pattern (low fat, increased fruit/vegetables) | ⇆ | ? | ? |
| Alcohol | ↑ | ? | ? |
*
Evidence based on one to two studies in each lifestyle factor.
†
Double symbol indicates strong evidence, with most published studies indicating associations between obesity and poorer survival.
‡
Few cohort studies of weight loss and survival, but Women's Intervention Nutrition Study result with 6 lb intervention versus control difference at median 60 months follow-up suggests weight loss could be associated with improved survival.