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. 2010 Jun 9;24(8):1559–1568. doi: 10.1210/me.2009-0439

Figure 1.

Figure 1

Gross phenotype of TEC1KO embryos. A, E14.5 TEC1KO embryos (right) are indistinguishable from WT littermates (left). Although the mutant appears slightly smaller than the WT type in this figure, this was not a consistent finding. B, E17.5 TEC1KO pups (n = 11) weighed significantly more than WT littermates (n = 35) (P = 0.0036). C, The mutants (right) exhibited increased swelling and rounding of the frontonasal (black arrow) and maxillary bones (white arrow) compared with WT embryos of the same age (left). D, Within 1–2 h after delivery, TEC1KO neonates showed signs of asphyxiation, such as facial cyanosis. Abdominal distention (arrow) results from swallowing air during attempts to breathe. *, P ≤ 0.01.