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MiTF-CX increases MiTF-CX promoter activity. HEK293 (panel A) or human cervical stromal cells (panel B) were transfected with vector or a 2.1-kb MiTF-CX promoter reporter construct in the presence of expression constructs for control (CTL), MiTF-CX, or mutated MiTF-CXmi. Thereafter, luciferase activity normalized to β-galactosidase was determined. *, P ≤ 0.01. Inset, Immunoblot analysis of cells transfected with MiTF-CX, CXmi, or control vector.
