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Decreased β-cell but increased neuronal gene expression in compound-mutant β-cells. Genes with the greatest fold of reduction (−29.4-fold) are listed at the top, whereas genes with the greatest fold of induction (+19.5-fold) are at the bottom. The heat bar on the left indicates DM/CT ratio of individual gene’s expression level in double-mutant (DM) over the level in control (CT) islets. Fold changes are indicated in color-coded boxes next to the corresponding genes.
