Skip to main content
. 2010 Jul 7;24(9):1765–1781. doi: 10.1210/me.2009-0487

Figure 4.

Figure 4

The ERK, PI3-kinase, and EGFR pathways are not involved in LHR signaling to cofilin. Preovulatory granulosa cells were not treated or treated with DMSO (VEH) for 1.5 h, 50 μm PD98059 (PD) for 1.5 h, or 12.5 μm LY294002 (LY) for 1 h and then left untreated (- - -) or treated with hCG for 10 or 30 min. Western blots are representative of three separate experiments. Graphs represent densitometric analysis of phospho (p)-cofilin Western values divided by total cofilin values to account for loading differences. Values are expressed as fold change from that of untreated controls, which has been set to a value of one. Values are the mean ± se of three separate experiments. #, P > 0.01.