Table 1.
Affymetrix (rat genome array) expression profiling comparing uninduced cells to cells expressing active fragment of human OASIS for 24 h
| Gene ID | Fold change (mean) | Description/putative function |
|---|---|---|
| 294103 | 23.54 | Papss2, sulfate conjugation |
| 25107 | 20.09a | Avrp1A, inositol-calcium signaling |
| 360959 | 8.32 | HtrA3, cytoskeletal remodeling, ERAD, inhibitor of TGF-β signaling |
| 312607 | 6.77 | Pdzrf3, ubiquitin protein ligase activity |
| 287877 | 5.34 | P5cr1, arginine and proline metabolism |
| 294048 | 5.2 | Pi3kap, signaling |
| 297894 | 4.3a | Matn1 cartilage matrix protein |
| 498609 | 4.28 | Lpar2, signal transduction |
| 360611 | 4.22 | Copζ2, protein transport |
| 25027 | 3.4 | Slc16a1, transporter |
| 29241 | 3.18a | Adcy8, adenylyl cyclase 8 |
| 282712 | 3.03 | Slc6a15, transporter |
| 315131 | 3.03 | Kdelr3, protein transport |
| 79247 | 2.85a | Htr5b, serotonin receptor |
| 304322 | 2.66a | Chst12, carbohydrate sulfotransferase |
| 29643 | 2.54 | Sv2c, protein secretion/transport |
| 64313 | 2.39 | Oat, proline metabolism |
| 690050 | 2.33 | Tpmt, thiopurine methylation |
| 680493 | 2.1 | Cd3εap, Notch signaling |
Common genes induced in three independent experiments greater than 2-fold are shown. ERAD, ER-associated degradation.
a
Genes induced in two of three experiments.