Table 5.
Parameters | Non-EIAEDs (n = 76)a (150 mg/d) | Phase I/IIb (n = 18) (150 mg/d) |
---|---|---|
Cmax (ng/mL) | 872 (±399) | 983 (±500) |
Tmax (h) | 3.0 (±1.9) | 4.1 (±3.1) |
AUC0–24 (µg h/mL) | 11.86 (±5.01) | 12.94 (±4.56) |
Css min (µg/mL) | 0.98 (±0.54) | 1.00 (±0.67) |
aCurrent study.
bHerbst et al.31.