Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Enzastaurin-related adverse events from 118 patients
| Toxicity | Grade 2 | Grade 3 | Grade 4 | Grade 5 | Total Grade ≥ 3 |
|---|---|---|---|---|---|
| Thrombosis/thrombus/embolism | 1 | 3 | 11 | 14 (12%) | |
| Platelets | 8 | 7 | 2 | 9 (7.6%) | |
| Hemorrhage, CNS | 6 | 2 | 8 (6.7%) | ||
| Hemorrhage, other | 2 | 1 | 3 (2.5%) | ||
| ALT, SGPT | 8 | 3 | 1 | 4 (3.4%) | |
| AST, SGOT | 3 | 1 | 1 | ||
| Prolonged QTc interval | 5 | 0 | |||
| Bilirubin (hyperbilirubinemia) | 4 | 0 | |||
| Diarrhea | 2 | 0 | |||
| Nausea | 1 | 0 | |||
| Alkaline phosphatase | 1 | 0 | |||
| Hypoalbuminemia | 1 | 0 | |||
| Cardiac ischemia | 1 | 0 |
