(A and B) Virus-treated animals maintained eating and grooming habits and normal weights whereas PBS-treated animals became cachectic. Before tumor inoculation the average weights of the three groups of animals were the same (early treatment, 22.0 ± 1.2 g; late treatment, 21.8 ± 1.3 g; control, 22.6 ± 0.36 g). After 22 days, the control PBS-treated group lost a significant amount of weight compared with animals in both GLV-1h68-treated groups (early treatment, 21.9 ± 0.2 g; late treatment, 23.7 ± 1.0 g; PBS, 17.8 ± 0.9 g) (Student t test).