Fig. 5.

Stable FasL knock-down promotes T-cell infiltration in intracranial gliomas. (A) Tumor sections from 9L transfected cell lines implanted into the brains of Fisher rats were stained for the presence of CD3. (B) The number of CD3-positive cells was quantified using computer-based methodology as described in Materials and Methods. The results indicate a significantly higher number of CD3 positive infiltrating cells in sections from 9L FasL knock-down tumors than in 9L wild-type or 9L shSCR tumors.