Table 1.
Summary of immunohistochemical features of the xenograft tumors during in vivo subtransplantations
| Target phenotypes | Marker | Patient tumor | Xenograft tumors |
|
|---|---|---|---|---|
| P-I | P-III | |||
| Human identity | MT | +100% | +100% | +100% |
| Proliferation | Ki67 | +60% | ++ 70% | ++ 70% |
| Neuron precursor | Nestin | +80% | ++ 100% | ++ 100% |
| Neuron-early | TuJ-1 | ++ 50%–80% | ++ 50%–70% | ++ 50% |
| Neuron mature | MAP2 | +isolated | ++ 50% | ++ 50% |
| Neuron mature | SYP | (−) | +30% | +5%–10% |
| Astrocyte | GFAP | +isolated | +40% | ++ 10%, +60% |
| Epithelial membrane antigen | EMA | (−) | (−) | (−) |
| Angiogenesis | VWF | 5–10/HP | 5–10/HP | >10/HP |
| Angiogenesis | VEGF | +70% | ++ 20%, + 60% | +80% |
| Angiogenesis | VEGFR1 | ++ 30%–50% | ++ 60% | ++ 50% |
| Intermediate filament | VIM | +100% | ++ + 100% | ++ + 100% |