Table 1.
Clinical characteristics of study sample
| WHO grade | n | Sex (M/F) | Histology/WHO grade | n | Median age (y) | Median PFS (m) | Number of tumor regrowth | Median OS (m) | Alive at LO |
|---|---|---|---|---|---|---|---|---|---|
| 3 | 23 | 16/7 | AA/3 | 18 | 45 (18–71) | 9.3 (1.0–28.7) | 5/18 | 12.1 (4.4–28.7) | 2/18 |
| AOA/3 | 3 | 56 (21–68) | 25.1 (23.5–41.0) | 2/3 | 25.7 (25.1–41.0) | 2/3 | |||
| AO/3 | 2 | 34 (32–36) | 10.3 (10.3–28.2) | 2/2 | 10.3 (10.3–28.2) | 1/2 | |||
| 4 | 43 | 24/19 | pGBM/4 | 35 | 59 (18–72) | 9.8 (2.0–22.8) | 17/35 | 10.6 (2.4–22.8) | 3/35 |
| sGBM/4 | 8 | 47 (22–61) | 6.9 (1.1–11.9) | 4/8 | 7.0 (1.1–17.5) | 1/8a |
Abbreviations: n, case number; M, male; F, female; y, years; m, months; LO, last observation; AA, anaplastic astrocytoma; AOA, anaplastic oligoastrocytoma; AO, anaplastic oligodendroglioma; pGBM, primary glioblastoma; sGBM, secondary glioblastoma.
aDeath of 1 patient not tumor related.