Fig. 1.

Complete remission of RG-2 gliomas after H-1PV treatment MR images of animal #100 (A1 to A4) and #712 (B1 to B3) at different time points. For each examination, 3 coronary sections are shown. Tumor volumes defined by the area of contrast enhancement progressively decreased after H-1PV injection. Animal #100 was infected with H-1PV intratumorally (A1) and examined on days 3, 7, and 150 p.i. (A2, A3, and A4, respectively). Examination dates for animal #712, which was infected intravenously (B1), were days 7 and 28 p.i. (B2 and B3). Both animals have survived for more than 6 months and without tumor recurrence.