Table 1.
Animal ID* | Days p.i. | Specimen or organ |
||||||||
---|---|---|---|---|---|---|---|---|---|---|
Tumor | Brain peritumoral | Brain contralateral | Cerebellum | Heart | Lung | Liver | Spleen | Kidney | ||
A | 2 | + | + | neg | neg | + | + | + | + | + |
B | 3 | + | + | + | + | + | + | + | + | + |
C | 3 | + | + | + | + | + | + | + | + | + |
D | 4 | + | + | + | + | + | + | + | + | + |
E | 8 | + | + | + | neg | neg | + | + | + | + |
F | 10 | + | + | + | neg | neg | neg | + | + | neg |
G | 11 | + | + | neg | neg | neg | neg | + | neg | + |
H | 14 | neg | neg | neg | neg | neg | neg | neg | neg | neg |
*A separate group of 8 tumor-bearing animals was analyzed for the presence of H1PV DNA (+), at various time points after intratumoral injection of H-1PV (p.i.). “neg”, no viral DNA detectable.