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. 2010 Sep 16;6(9):e1000923. doi: 10.1371/journal.pcbi.1000923

Table 2. Summary of performance.

subset Inline graphic Inline graphic Inline graphic Inline graphic LOD Inline graphic-value
Conservation (Inline graphic) 741436 14211 459030 10273 0.22 Inline graphic
Conservation (Inline graphic) 741436 14211 144591 4892 0.82 Inline graphic
Conservation (Inline graphic) 741436 14211 53443 2402 1.23 Inline graphic
Contact 70589 2747 59079 2522 0.13 Inline graphic
Correlation 741436 14211 62365 1988 0.73 Inline graphic
Correlation (Inline graphic) 287029 3961 16271 388 0.78 Inline graphic
Correlation (Inline graphic) 599322 9328 49254 1463 0.93 Inline graphic
Correlation (Inline graphic) 688790 11799 61802 1955 0.88 Inline graphic
Correlation, non-contact 70589 2747 4960 252 0.38 Inline graphic

Inline graphic-values were computed using Fisher's exact test. Inline graphic: number of all residues; Inline graphic: number of disease mutations; Inline graphic: number of correlated positions; Inline graphic: number of correlated residues affected by disease-associated mutations.