Table 1. Summary of Microarray Results for Components of Desmosomes and Adherens Junctions.
P-value | Fold-changea | Affymetrix probe IDb | Gene symbol | Gene name | Synonyms | Complex |
0.017 | −7.81 | 1426911_at | Dsc2 | Desmocollin 2 | Desmosome | |
0.027 | −7.52 | 1439476_at | Dsg2 | Desmoglein 2 | Desmosome | |
0.053 | −12.61 | 1435494_s_at | Dsp | Desmoplakin | Desmosome | |
0.019 | −14.03 | 1449799_s_at | Pkp2 | Plakophilin 2 | Desmosome | |
0.029 | −12.99 | 1448261_at | Cdh1 | Cadherin 1 | E-cadherin | Adherens junction |
0.181 | −1.33 | 1437807_x_at | Ctnna1 | Catenin alpha 1 | Alpha E catenin | Adherens junction |
0.795 | −1.09 | 1430533_a_at | Ctnnb1 | Catenin beta 1 | Beta catenin | Adherens junction |
0.444 | 1.29 | 1445830_at | Ctnnd1 | Catenin delta 1 | P120 catenin | Adherens junction |
0.852 | 1.30 | 1426873_s_at | Jup | Junction plakoglobin | Gamma catenin | Adherens junction; desmosome |
Fold-change represents the widely invasive carcinoma type-2 (IC2) class as compared to the non-invasive islet tumor (IT) class of RIP1-Tag2 tumor lesions.
Affymetrix probe ID corresponds to the Mouse Genome 430 2.0 Array.