Table 3. Mouse infectivity of Borrelia burgdorferi with overproduction of Rrp2-N or Pta.
Strain | Ear* | No. of cultures positive/total No. | No. of mice positive/total No. of mice | |||
Skin | Joint | Heart | All sites | |||
B31-A3 | ||||||
105 | 3/3 | 3/3 | 3/3 | 3/3 | 9/9 | 3/3 |
103 | 9/10 | 9/10 | 9/10 | 9/10 | 27/30 | 9/10 |
A3/vRrp2-N | ||||||
105 | 2/3 | 2/3 | 2/3 | 2/3 | 6/9 | 2/3 |
103 | 0/5 | 1/5 | 1/5 | 1/5 | 3/15 | 1/5 |
A3/vRrp2-ND52A | ||||||
103 | 5/5 | 5/5 | 5/5 | 5/5 | 15/15 | 5/5 |
A3/vPta | ||||||
103 | 4/8 | 4/8 | 3/8 | 4/8 | 11/24 | 4/8 |
*Ear punch biopsies were examined at day 10 and other tissues were examined at day 20 post inoculation.