Table 2.
Quantitative FACS analysis of MRP3 expression by biopsies, cell lines, and established xenografts with MAb 16A11
Diagnosis | Positive cases/Total cases | Percent | Estimated number of MRP3 molecules per cell |
---|---|---|---|
Cell Lines | |||
GBM adult | 6/7 | 86 | 0.1-4.9 × 105 (med. = 1.9 × 105) |
MED pediatric | 5/5 | 100 | 0.7--2 × 105 (med. = 1 × 105) |
Biopsies | |||
AA adult | 3/6 | 50 | 1.7--2.7 × 104 |
GBM adult | 22/27 | 82 | 0.17--6.5 × 105 (med. = 6.5 × 104) |
Xenografts | |||
GBM adult | 4/7 | 57 | 0.2--2.1 × 105 |
MED pediatric | 2/3 | 67 | 1.6--2.5 × 104 |