Table 3.
Distribution of the genotypes, alleles frequencies and odd ratio of the β2 Gln27Glu polymorphism in overweight and control subjects.
| Genotype | Sex |
Control M:35 F: 80 T = 115 |
Overweight M:28 F: 40 T = 68 |
Obese M:46 F: 100 T = 146 |
χ2 Odds ratio(95% CI) |
P- value |
|---|---|---|---|---|---|---|
| Genotype Frequency | ||||||
| Gln\Gln | M | 24 (68.57) | 17 (60.7) | 27 (58.67) |
χ2 M= 1.19 F= 2.23 |
P value M = 0.880 |
| F | 51 (63.75) | 26 (65) | 60 (60) | |||
| T | 75(65.2) | 43(63.2) | 87(59.6) | |||
| Gln\Glu | M | 5 (14.28) | 5 (17.58) | 7 (15.21) |
Odds ratio (95% CI) Control vs OW 1.1 (0.5, 2.39) |
F = 0.693 |
| F | 13 (16.25) | 6 (15) | 12 (12) | |||
| T | 18(15.7) | 11(16.2) | 19(13.0) | |||
| Glu\Glu | M | 6 (17.12) | 6 (21.42) | 12 (26) |
Odds ratio (95% CI) Control vs Obese 1.567(0.85,2.87) |
P value for Odds ratio in normal vs overweight and normal vs obese: P > 0.05 |
| F | 16 (20) | 8 (20) | 28 (28) | |||
| T | 22(19.1) | 14(20.6) | 40(27.4) | |||
| Allele Frequency | ||||||
| Allele Gln27 | T | 73.0% | 71.3% | 66.1% |
Odds ratio (95% CI) Control vs OW 0.95 (0.71, 1.27) |
P = 0.70 |
| Allele Glu27 | T | 27.0% | 28.7% | 33.9% |
Odds ratio (95% CI) Control vs Obese 0.87 (0.74, 1.2) |
P = 0.09 |
NOTE: M= Male; F= Female; T= Total; OW= Overweight; CI: Confidence interval