Table 2.
Comparison of characteristics of patients that are or are not part of a transmission cluster.
| ∈ cluster | ∉ cluster | Multivariate Bin. Log. Regression | ||||
|---|---|---|---|---|---|---|
| Count | Count | p-value | ODDS ratio | 95% CI | p-value | |
| # Patienten (n = 506) | 169 (33.4%) | 337 (66.6%) | ||||
| Subtype B | 143/169 (84.6%) | 159/337 (47.2%) | < 0.001 | - | ||
| Homosexual transmission | 125/150 (83.3%) | 117/258 (45.3%) | < 0.001 | 3.1 | 1.8 - 5.4 | < 0.001 |
| HBV+ | 56/167 (33.5%) | 132/324 (40.7%) | 0.12 | - | ||
| HCV+ | 14/167 (8.4%) | 20/325 (6.2%) | 0.356 | |||
| Syphilis+ | 68/169 (40.2%) | 72/331 (21.8%) | < 0.001 | - | ||
| Chlamydia+ | 61/151 (40.4%) | 66/234 (28.2%) | 0.013 | - | ||
| Gender (male) | 154/169 (91.1%) | 219/337 (64.4%) | < 0.001 | - | ||
| Caucasian origin | 158/166 (95.2%) | 195/335 (58.2%) | < 0.001 | 14.5 | 4.2 - 49.9 | < 0.001 |
| DRM | 12/169 (7.1%) | 21/337 (6.2%) | 0,709 | |||
| PHI | 34/162 (21.0%) | 38/302 (12.6%) | 0.017 | - | ||
| Median (IQR) | Median (IQR) | p-value | ||||
| CD4+ T cells (cells/μl) | 419.5 (311-580) | 351 (192-550) | 0.002 | - | ||
| Age (years) | 36 (31-42) | 38 (32-45) | 0.067 | 0.9 | 0.92 - 0.97 | < 0.001 |
Values are given as counts per number of patients of which data was available. For the multivariate analysis, odds ratios are given with regard to being a member of a cluster (∈ cluster). The p-value for the Hosmer-Lemeshow test for the multivariate model is 0.876.
HBV, Hepatitis B Virus; HCV, Hepatitis C Virus; DRM, Drug Resistant Mutations; PHI, Primary HIV Infection; IQR, interquartile range; CI, confidence interval.