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. Author manuscript; available in PMC: 2010 Sep 16.
Published in final edited form as: J Alzheimers Dis. 2010 Jan 1;21(3):871–885. doi: 10.3233/JAD-2010-091693

Table 2.

Activation foci for famous versus unfamiliar name subtraction (Famous > Unfamiliar)*

Region # Region Cortical Component Loadings Hippocampal Component Loadings x y z Stable Group Volume Declining Group Volume
1 Bilateral Posterior Cingulate Cortex, Precuneus 0.884 0.257 −0.9 −52.4 24.6 37.05
2 Left Angular Gyrus 0.889 0.266 −45.4 −55.9 23.7 26.14 1.44
3 Left Superior Frontal Gyrus 0.805 0.018 −17.8 29.5 41 30.84
4 Right Angular Gyrus 0.815 0.275 46.2 −59.6 27.1 18.68
6 Right Superior, Middle Frontal Gyrus 0.839 0.009 22.5 16.5 46.8 3.2
5 Left Parahippocampal Gyrus, Hippocampus 0.269 0.898 −21.9 −21 −10.7 2.29
7 Right Parahippocampal Gyrus, Hippocampus 0.053 0.946 23.9 −23.2 −11.6 0.86
8 Right Cerebellum (Crus 1) 0.425 0.268 11.3 −74.8 −21.9 1.03

Note: Critical value (2*rcrit,p = .01) used to identify significant component loadings was 0.560 [80].

*

PCA conducted on four negative activation (Unfamiliar > Familiar) clusters (Left Precentral Gyrus; Bilateral Supplementary Motor Area; Right Insula; Left Middle Occipital Gyrus) revealed one component that did not predict decline; this component was dropped from subsequent analyses.