Table 2.
Region # | Region | Cortical Component Loadings | Hippocampal Component Loadings | x | y | z | Stable Group Volume | Declining Group Volume |
---|---|---|---|---|---|---|---|---|
1 | Bilateral Posterior Cingulate Cortex, Precuneus | 0.884 | 0.257 | −0.9 | −52.4 | 24.6 | 37.05 | |
2 | Left Angular Gyrus | 0.889 | 0.266 | −45.4 | −55.9 | 23.7 | 26.14 | 1.44 |
3 | Left Superior Frontal Gyrus | 0.805 | 0.018 | −17.8 | 29.5 | 41 | 30.84 | |
4 | Right Angular Gyrus | 0.815 | 0.275 | 46.2 | −59.6 | 27.1 | 18.68 | |
6 | Right Superior, Middle Frontal Gyrus | 0.839 | 0.009 | 22.5 | 16.5 | 46.8 | 3.2 | |
5 | Left Parahippocampal Gyrus, Hippocampus | 0.269 | 0.898 | −21.9 | −21 | −10.7 | 2.29 | |
7 | Right Parahippocampal Gyrus, Hippocampus | 0.053 | 0.946 | 23.9 | −23.2 | −11.6 | 0.86 | |
8 | Right Cerebellum (Crus 1) | 0.425 | 0.268 | 11.3 | −74.8 | −21.9 | 1.03 |
Note: Critical value (2*rcrit,p = .01) used to identify significant component loadings was 0.560 [80].
PCA conducted on four negative activation (Unfamiliar > Familiar) clusters (Left Precentral Gyrus; Bilateral Supplementary Motor Area; Right Insula; Left Middle Occipital Gyrus) revealed one component that did not predict decline; this component was dropped from subsequent analyses.