Figure 6.

Results of modeling of the equatorial intensity using disorder parameters obtained from electron microscopy: RMSD for the thin and thick filaments were taken as their average deviations, Δa, Δm (Table 1) multiplied by a factor of 1.13. Model of cold relaxed state (thin line) was obtained using cold relaxed disorder parameters (Table 1) and by assuming that the width of the myosin head halo is 9 nm. The hot state (thick line) was modeled using a 6-nm halo and hot disorder parameters. The dashed line corresponds to a state where myosin heads are closely packed (6-nm halo), but the disorder parameters are the same as those for the cold state.