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. 2010 Sep 22;99(6):1818–1826. doi: 10.1016/j.bpj.2010.06.066

Figure 5.

Figure 5

Myosin X steps in all directions from a common intermediate. On a fascin-actin bundle, the dwell time of myosin X before a step in any direction is part of the same single-exponential distribution. (Black solid trace) Survivor function of dwell times preceding steps in any direction (n = 363 dwells, 9.2 ± 0.5 s, mean ± SE). (Cyan solid trace) Positive x steps (along the x axis; n = 122 dwells, 8.5 ± 0.8 s). (Cyan dashed trace) Negative x steps (n = 22 dwells, 11.2 ± 2.6 s). (Gray solid trace) Positive y steps (along the y axis; n = 59 dwells, 8.1 ± 1.4 s). (Gray dashed trace) Negative y steps (n = 58 dwells, 10.6 ± 1.4 s). (Red trace) Quadrant I steps (n = 45 dwells, 7.2 ± 1.1 s). (Blue trace) Quadrant II steps (n = 9 dwells, 10.9 ± 3.9 s). (Magenta trace) Quadrant III steps (n = 8 dwells, 7.1 ± 2.1 s). (Green trace) Quadrant IV steps (n = 40 dwells, 9.7 ± 1.8 s). We detected no significant statistical differences among these nine distributions by a Wilcoxon rank-sum test at the α = 0.5 level.