Table 3.
The comparison of the rate of sustained virological response of patients with genotype 1 receiving a dose of 80% or more of pegylated interferon α-2b plus 60% or more of ribavirin and the reduced dosage group n (%)
Male |
Female |
Total |
||||
n | SVR | n | SVR | n | SVR | |
Group A | ||||||
Minimum acceptable | 168 | 116 (69.0) | 110 | 69 (62.7) | 278 | 185 (66.5) |
Reduced | 206 | 73 (35.4) | 201 | 66 (32.8) | 407 | 139 (34.2) |
Total | 374 | 189 (50.5) | 311 | 135 (43.4) | 685 | 324 (47.3) |
Group B | ||||||
Minimum acceptable | 31 | 15 (48.4) | 31 | 13 (41.9) | 62 | 28 (45.2) |
Reduced | 91 | 18 (19.8) | 100 | 12 (12.0) | 191 | 30 (15.7) |
Total | 122 | 33 (27.0) | 131 | 25 (19.1) | 253 | 58 (22.9) |
Minimum acceptable: patients who received 80% or more of the target dose of pegylated interferon (IFN) α-2b and 60% or more of ribavirin (RBV). Reduced: Patients who received less than 80% of pegylated IFN α-2b and less than 60% of RBV. SVR: Sustained virological response.